Tetramethylpyrazine promotes the proliferation and migration of brain endothelial cells

@inproceedings{Zhang2014TetramethylpyrazinePT,
  title={Tetramethylpyrazine promotes the proliferation and migration of brain endothelial cells},
  author={Mingshun Zhang and Feng Gao and Fengmeng Teng and Chunbing Xing Junfu Zhang},
  booktitle={Molecular medicine reports},
  year={2014}
}
The aim of the present study was to investigate the role of tetramethylpyrazine (TMP), one of the alkaloids isolated from the Chinese herb Chuanxiong, on the proliferation and migration of brain endothelial cells. A different dosage of TMP was employed to stimulate the mouse microvascular cell line bEnd.3 in vitro. TMP at lower concentrations (0.25 ng/ml), however not at high concentrations (100 ng/ml) could promote the proliferation and migration of endothelial cells, which was further… CONTINUE READING
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