Tetramer Enrichment Reveals the Presence of Phenotypically Diverse Hepatitis C Virus-Specific CD8+ T Cells in Chronic Infection

@inproceedings{Nitschke2015TetramerER,
  title={Tetramer Enrichment Reveals the Presence of Phenotypically Diverse Hepatitis C Virus-Specific CD8+ T Cells in Chronic Infection},
  author={Katja Nitschke and Tobias Flecken and Julia Schmidt and Emma Gostick and Matthias Marget and Christoph Neumann-Haefelin and H. E. Blum and David A. Price and Robert Thimme},
  booktitle={Journal of virology},
  year={2015}
}
UNLABELLED Virus-specific CD8(+) T cells are rarely detectable ex vivo by conventional methods during chronic hepatitis C virus (HCV) infection. In this study, however, we were able to detect and characterize HCV-specific CD8(+) T cells in all chronically HCV genotype 1a-infected, HLA-A*02:01-positive patients analyzed by performing major histocompatibility… CONTINUE READING