Tetrahymena as a Unicellular Model Eukaryote: Genetic and Genomic Tools
The tools for the use of Tetrahymena as a model eukaryote are described, including an overview of its life cycle, orientation to its evolutionary roots, and methodological approaches to forward and reverse genetics.
An olympian protozoan
This brief essay summarizes advances of ciliates of the genus Tetrahymena, which enabled the discovery of the telomeric DNA repeat, telomerase and self-splicing RNA, as well as figuring prominently in the recognition of histone modifications as an epigenetic mechanism.
Purification of Tetrahymena cytoskeletal proteins.
- Biology, ChemistryMethods in cell biology
Tetrahymena Comparative Genomics Sequencing Project
The comparative genome sequence made available by this project would be invaluable to the study of processes relevant to human health, such as chromatin structure, telomeres and telomerase, ciliary motility, RNAi, phagocytosis, regulated secretion, etc.
Perspectives on the ciliated protozoan Tetrahymena thermophila.
- BiologyMethods in cell biology
The Green Tetrahymena utriculariae n. sp. (Ciliophora, Oligohymenophorea) with Its Endosymbiotic Algae (Micractinium sp.), Living in Traps of a Carnivorous Aquatic Plant
- Biology, Environmental ScienceThe Journal of eukaryotic microbiology
The morphological and molecular description of the first green representative of the Tetrahymena utriculariae n.
Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote
- BiologyPLoS biology
The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct…
HAP2-Mediated Gamete Fusion: Lessons From the World of Unicellular Eukaryotes
- BiologyFrontiers in Cell and Developmental Biology
The current state of knowledge around how mating types from these algal and ciliate systems recognize, adhere and fuse to one another, current gaps in their understanding of HAP2-mediated gamete fusion, and opportunities for applying what the authors know in practical terms are summarized.
N6-methyladenine DNA modification in the unicellular eukaryotic organism Tetrahymena thermophila.
- BiologyEuropean journal of protistology