Tetrahydrozoline (Visine®) concentrations in serum and urine during therapeutic ocular dosing: A necessary first step in determining an overdose
@article{Carr2011TetrahydrozolineC, title={Tetrahydrozoline (Visine{\textregistered}) concentrations in serum and urine during therapeutic ocular dosing: A necessary first step in determining an overdose}, author={Mary E. Carr and Kristin M. Engebretsen and Benjamin Wen Yang Ho and Christopher P. Anderson}, journal={Clinical Toxicology}, year={2011}, volume={49}, pages={810 - 814} }
Introduction. No information exists on therapeutic or toxic concentrations of tetrahydrozoline, which has been reported to be used in drug facilitated sexual assaults. The primary aim of this investigation was to establish baseline therapeutic serum and urine concentrations in a sample of healthy volunteers. Methods. Ten healthy volunteers consented to have two drops of Original Visine® eye drops (0.05% tetrahydrozoline solution) placed directly into the conjunctival sac of each eye, 30 s apart…
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