Tetrad analysis shows that gene conversion is the major mechanism involved in mutation at the human minisatellite MS1 integrated in Saccharomyces cerevisiae.

@article{Berg2000TetradAS,
  title={Tetrad analysis shows that gene conversion is the major mechanism involved in mutation at the human minisatellite MS1 integrated in Saccharomyces cerevisiae.},
  author={I Cecilia Hahn Berg and H{\aa}kan Cederberg and Ulf Rannug},
  journal={Genetical research},
  year={2000},
  volume={75 1},
  pages={1-12}
}
Minisatellites are arrays of tandemly repeated DNA sequences which occur at thousands of locations in the human genome. They are frequently hypervariable with respect to allele length as a result of high rates of complex and incompletely understood recombination-based germline mutation events that alter the repeat copy number. MS1 is one of the most… CONTINUE READING