Tetraaddition of PhLi to a ketocalixarene derivative.


[reaction: see text] Reaction of a ketocalixarene with 2.2 equiv or an excess of PhLi affords diaddition and tetraaddition products, respectively. Ionic hydrogenation of the tetraalcohol 8a yields a calix[4]arene monosubstituted by phenyl groups at all four methylene bridges. 


Cite this paper

@article{Kuno2007TetraadditionOP, title={Tetraaddition of PhLi to a ketocalixarene derivative.}, author={Lev Kuno and Noa Seri and Silvio E. Biali}, journal={Organic letters}, year={2007}, volume={9 8}, pages={1577-80} }