Tetherin inhibits prototypic foamy virus release

@inproceedings{Xu2011TetherinIP,
  title={Tetherin inhibits prototypic foamy virus release},
  author={Fengwen Xu and Juan Tan and Ruikang Liu and Dan Xu and Yue Li and Yunqi Geng and Chen Liang and Wentao Qiao},
  booktitle={Virology Journal},
  year={2011}
}
BackgroundTetherin (also known as BST-2, CD317, and HM1.24) is an interferon- induced protein that blocks the release of a variety of enveloped viruses, such as retroviruses, filoviruses and herpesviruses. However, the relationship between tetherin and foamy viruses has not been clearly demonstrated.ResultsIn this study, we found that tetherin of human, simian, bovine or canine origin inhibits the production of infectious prototypic foamy virus (PFV). The inhibition of PFV by human tetherin is… CONTINUE READING

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