Tetanus toxin-induced seizures in infant rats and their effects on hippocampal excitability in adulthood.

@article{Lee1995TetanusTS,
  title={Tetanus toxin-induced seizures in infant rats and their effects on hippocampal excitability in adulthood.},
  author={Chong Lek Lee and Richard A. Hrachovy and Karen L. Smith and James D. Frost and John W. Swann},
  journal={Brain research},
  year={1995},
  volume={677 1},
  pages={97-109}
}
A new experimental model of developmental epilepsy is reported. Behavioral and EEG features of seizures produced by unilateral intrahippocampal injection of tetanus toxin in postnatal day 9-11 rats, are described. Within 24-72 h of tetanus toxin injection, rat pups developed frequent and often prolonged seizures which included combinations of repetitive wet dog shakes, and wild running-jumping seizures. Intrahippocampal and cortical surface EEG recordings showed that coincident with these… CONTINUE READING
13 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…