Testosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure.

@article{Davis2012TestosteroneSI,
  title={Testosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure.},
  author={Deborah D. Davis and Arnaldo Lopez Ruiz and Licy L. Yanes and Radu Iliescu and Kuichang Yuan and Mohadetheh Moulana and Lorraine C. Racusen and Jane F. Reckelhoff},
  journal={Hypertension},
  year={2012},
  volume={59 3},
  pages={
          726-31
        }
}
Androgen levels are lower in obese men as compared with normal weight individuals. However, there are no safety data regarding the chronic use of androgen supplements in middle-aged men. The present study was undertaken to determine the cardiovascular and metabolic effects of chronic (10 weeks) testosterone treatment in male obese Zucker rats, starting at 22 weeks of age, when testosterone levels were significantly decreased. Testosterone supplements increased plasma levels, 10-fold in both… CONTINUE READING

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