Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia.

@article{Rhoden2003TestosteroneRT,
  title={Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia.},
  author={Ernani Lu{\'i}s Rhoden and Abraham Morgentaler},
  journal={The Journal of urology},
  year={2003},
  volume={170 6 Pt 1},
  pages={2348-51}
}
PURPOSE One of the greatest concerns among clinicians regarding testosterone replacement therapy (TRT) is the fear of causing or promoting prostate cancer. We evaluated prostatic changes in hypogonadal men with and without high grade prostatic intraepithelial neoplasia (PIN), which is considered a prostatic precancerous lesion, after 1 year of TRT. MATERIALS AND METHODS A total of 75 hypogonadal who completed 12 months of TRT were studied. All underwent prostate biopsy prior to initiating… CONTINUE READING