Testosterone inhibits facilitating effects of parenting experience on parental behavior and the oxytocin neural system in mice

  title={Testosterone inhibits facilitating effects of parenting experience on parental behavior and the oxytocin neural system in mice},
  author={Shota Okabe and Kanako Kitano and M. Nagasawa and K. Mogi and T. Kikusui},
  journal={Physiology & Behavior},
  • Shota Okabe, Kanako Kitano, +2 authors T. Kikusui
  • Published 2013
  • Psychology, Medicine
  • Physiology & Behavior
  • Parental behavior in mammals is facilitated by sensory experiences from infant, and by endocrine hormones. However, the interactions between these factors in the parental behavior of nonreproductive adults are not understood. We examined the interactive effects of gonadal hormones and the experience of repeated pup exposure on parental behavior in sexually naive mice. We also compared oxytocin (OT) expression levels in the paraventricular nucleus of the hypothalamus to behavioral outcomes… CONTINUE READING
    27 Citations
    Pup exposure facilitates retrieving behavior via the oxytocin neural system in female mice
    • 26
    Effects of neonatal oxytocin manipulation on development of social behaviors in mice
    • 26
    Paternal Retrieval Behavior Regulated by Brain Estrogen Synthetase (Aromatase) in Mouse Sires that Engage in Communicative Interactions with Pairmates
    • 13
    • PDF
    Testosterone, oxytocin, and the development of human parental care
    • 22
    • PDF
    Effects of oxytocin administration on salivary sex hormone levels in autistic and neurotypical women
    • 1
    Salivary sex hormone levels following oxytocin administration in autistic and typical women
    • PDF


    Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors
    • 562
    • PDF
    Induction of maternal behavior in virgin rats after intracerebroventricular administration of oxytocin.
    • C. Pedersen, A. Prange
    • Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1979
    • 710
    • PDF
    Gonadal Steroids have Paradoxical Effects on Brain Oxytocin Receptors
    • 105
    Oxytocin and the Development of Parenting in Humans
    • 335
    • PDF
    Steroidal influences on pup-killing behavior in mice
    • B. Svare
    • Chemistry, Medicine
    • Hormones and Behavior
    • 1979
    • 25
    Sex differences in the parental behavior of rodents
    • 180