Testosterone increases lipolysis and the number of beta-adrenoceptors in male rat adipocytes.

  title={Testosterone increases lipolysis and the number of beta-adrenoceptors in male rat adipocytes.},
  author={Xu-na Xu and Giovanni de Pergola and Per Bj{\"o}rntorp},
  volume={128 1},
The influence of androgen status on the regulation of lipolysis and number of beta-adrenoceptors in isolated adipocytes was studied in male rats. Castration resulted in decreased catecholamine-induced as well as forskolin-induced lipolysis. beta-adrenoceptor number, examined by a whole cell cyanopindolol binding assay, was also diminished to a similar extent. Testosterone treatment of castrated rats normalized lipolysis as well as beta-adrenoceptor number. These results demonstrate that… CONTINUE READING

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