Testosterone improves maze performance and induces development of a male hippocampus in females

@article{Roof1992TestosteroneIM,
  title={Testosterone improves maze performance and induces development of a male hippocampus in females},
  author={Robin L. Roof and Michael D. Havens},
  journal={Brain Research},
  year={1992},
  volume={572},
  pages={310-313}
}
In a combined behavioral and morphometric study, we observed a testosterone-related sexual dimorphism in the granule cell layer of the hippocampus of Sprague-Dawley rats that appears to be related to sex differences in spatial performance. This cell layer was larger and laterally asymmetrical in males. Neonatal testosterone treatment of females resulted in a more male-like hippocampus. These treated females also performed better than controls, and as well as males, on a spatial navigation task… CONTINUE READING

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