Testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus

  title={Testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus},
  author={Yvon Delville and Karim M. Mansour and Craig F. Ferris},
  journal={Physiology \& Behavior},

Vasopressin/Serotonin Interactions in the Anterior Hypothalamus Control Aggressive Behavior in Golden Hamsters

The present studies examine the neuroanatomical and neurochemical interaction between AVP and 5-HT at the level of the anterior hypothalamus (AH) in the control of offensive aggression in Syrian golden hamsters to suggest that5-HT inhibits fighting, in part, by antagonizing the aggression-promoting action of the AVP system.

Arginine‐vasopressin and the regulation of aggression in female Syrian hamsters (Mesocricetus auratus)

Contrary to what is observed in males, these data suggest that AVP in the AH may play an inhibitory role on aggression in female Syrian hamsters.

Repeated Anabolic-Androgenic Steroid Treatment during Adolescence Increases Vasopressin V1A Receptor Binding in Syrian Hamsters: Correlation with Offensive Aggression

It is suggested that adolescent anabolic steroid exposure may facilitate offensive aggression by increasing vasopressin V(1A) receptor binding in several key areas of the hamster brain.

Behavioral and Neurobiological Consequences of Social Subjugation during Puberty in Golden Hamsters

The results establish puberty as a developmental period sensitive to environmental stressors and show that changes in the vasopressin and serotonin systems can correlate with behavioral alterations, supporting the role of these two neurotransmitters in the regulation of aggression.



Medial amygdala and aggressive behavior: Interaction between testosterone and vasopressin

The absolute level of offense after arginine-vasopressin (AVP) treatment declined with time after castration indicating that the behavioral consequences of AVP in the Ame are at least partially independent of testosterone.

Intraspecific aggression in male hamsters is inhibited by intrahypothalamic vasopressin-receptor antagonist

The results confirm the earlier work showing that AVP-receptor antagonist reduces intraspecific aggression and suggest that hamsters microinjected into the anterior hypothalamus with an AVP, receptor antagonist also elicit less aggression from conspecifics.

Sex differences in hormonal responses of vasopressin pathways in the rat brain.

The results indicate that the sex difference in the steroid-sensitive AVP pathways depends on other factors besides circulating hormone levels in adulthood.

Ethology and pharmacology of hypothalamic aggression in the rat

  • M. Kruk
  • Biology, Psychology
    Neuroscience & Biobehavioral Reviews
  • 1992