Testosterone and Vascular Function in Aging

  title={Testosterone and Vascular Function in Aging},
  author={Rh{\'e}ure Alves Moreira Lopes and Karla Bianca Neves and Fernando S Carneiro and Rita C A Tostes},
  booktitle={Front. Physio.},
Androgen receptors are widely distributed in several tissues, including vascular endothelial and smooth muscle cells. Through classic cytosolic androgen receptors or membrane receptors, testosterone induces genomic and non-genomic effects, respectively. Testosterone interferes with the vascular function by increasing the production of pro-inflammatory cytokines and arterial thickness. Experimental evidence indicates that sex steroid hormones, such as testosterone modulate the synthesis and… CONTINUE READING
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