Testosterone and FSH have independent, synergistic and stage-dependent effects upon spermatogenesis in the rat testis

Abstract

Adult rats were hypophysectomized and treated with ethane dimethanesulphonate (EDS) selectively to eliminate the Leydig cells in the testis. By removing the source of endogenous gonadotrophins and androgens, the subsequent effects on the seminiferous epithelium were studied after 20 days of treatment with vehicle, or FSH (2x50 μg/day) or a low dose of… (More)
DOI: 10.1007/BF00338067

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@article{Kerr1992TestosteroneAF, title={Testosterone and FSH have independent, synergistic and stage-dependent effects upon spermatogenesis in the rat testis}, author={Jeffrey Kerr and Simon Maddocks and Richard M. Sharpe}, journal={Cell and Tissue Research}, year={1992}, volume={268}, pages={179-189} }