Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone.

  title={Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone.},
  author={Matthew J. Budoff and Susan S. Ellenberg and Cora E. Lewis and Emile R. Mohler and Nanette K Wenger and Shalender Bhasin and Elizabeth Barrett-Connor and Ronald S. Swerdloff and Alisa J Stephens-Shields and Jane A. Cauley and Jill P. Crandall and Glenn R. Cunningham and Kristine E Ensrud and Thomas M. Gill and Alvin M. Matsumoto and Mark E Molitch and Rine Nakanishi and Negin Nezarat and Suguru Matsumoto and Xiaoling Hou and Shehzad S. Basaria and Susan J. Diem and Christina Wang and Denise Cifelli and Peter J. Snyder},
  volume={317 7},
Importance Recent studies have yielded conflicting results as to whether testosterone treatment increases cardiovascular risk. Objective To test the hypothesis that testosterone treatment of older men with low testosterone slows progression of noncalcified coronary artery plaque volume. Design, Setting, and Participants Double-blinded, placebo-controlled trial at 9 academic medical centers in the United States. The participants were 170 of 788 men aged 65 years or older with an average of 2… CONTINUE READING