Testosterone, Estradiol, and Sex Hormone-Binding Globulin in Alzheimer's Disease: A Meta-Analysis.

@article{Xu2016TestosteroneEA,
  title={Testosterone, Estradiol, and Sex Hormone-Binding Globulin in Alzheimer's Disease: A Meta-Analysis.},
  author={Jing Xu and L Xia and Ning Hong Song and Shengdi Chen and Gang Wang},
  journal={Current Alzheimer research},
  year={2016},
  volume={13 3},
  pages={215-22}
}
BACKGROUND Previous studies suggested that plasma sex hormones may be implicated in the pathogenesis of Alzheimer's disease (AD). However, the relationship between sex hormones and AD remains unclear. OBJECTIVE To systematically review and quantitatively analyze studies observing plasma total testosterone (TT), estradiol (E2), and sex hormone-binding globulin (SHBG) levels among AD patients. METHODS Medline, EMBASE, the Cochrane Library, and PsycINFO were searched for studies published… CONTINUE READING