Testing the role of the cell-surface molecule Thy-1 in regeneration and plasticity of connectivity in the CNS.

Abstract

Thy-1 is a cell-surface signaling molecule of the Ig superfamily implicated in the regulation of neurite outgrowth, synaptic function and plasticity. There is, however, no consensus as to its precise function in the nervous system, and it remains unclear or untested as to what its role is in the development, maintenance and plasticity of neuronal… (More)

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