Testing the additional predictive value of high-dimensional molecular data

@inproceedings{Boulesteix2009TestingTA,
  title={Testing the additional predictive value of high-dimensional molecular data},
  author={Anne-Laure Boulesteix and Torsten Hothorn},
  booktitle={BMC Bioinformatics},
  year={2009}
}
While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years in biomedical research, the question of the additional predictive value of such data given that classical predictors are already available has long been under-considered in the bioinformatics literature. We suggest an intuitive permutation-based testing procedure for assessing the additional predictive value of high-dimensional… CONTINUE READING

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