Testing only donors with a prior history of pregnancy or transfusion is a logical and cost-effective transfusion-related acute lung injury prevention strategy.

@article{Powers2008TestingOD,
  title={Testing only donors with a prior history of pregnancy or transfusion is a logical and cost-effective transfusion-related acute lung injury prevention strategy.},
  author={Amy C. Powers and Christopher P Stowell and Walter Sunny Dzik and Susan L. Saidman and Heemoon Lee and Robert S. Makar},
  journal={Transfusion},
  year={2008},
  volume={48 12},
  pages={
          2549-58
        }
}
BACKGROUND Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related fatality reported to the Food and Drug Administration. Donor screening may reduce TRALI risk. This study sought to compare the efficacy and safety of different TRALI risk-reduction strategies at a hospital-based donor center. STUDY DESIGN AND METHODS Samples from 1053 donors who answered questions regarding pregnancy and transfusion history were tested for HLA Class I and II antibodies using a… CONTINUE READING

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