Testing of sunset yellow and orange II for genotoxicity in different laboratory animal species

@article{Wever1989TestingOS,
  title={Testing of sunset yellow and orange II for genotoxicity in different laboratory animal species},
  author={J. Wever and R. Muenzner and H. Renner},
  journal={Environmental and Molecular Mutagenesis},
  year={1989},
  volume={13}
}
The azo dyes Sunset Yellow and Orange II were gavaged to rodent species to check bile, urine, and fecal extracts for possible mutagenic activity in the Ames test or in bone marrow cells for clastogenicity using cytogenetic test systems. After oral application the dyes showed a negative response in bile, excrements, and bone marrow. When an exogenous metabolic activation was performed, increased revertant numbers using Salmonella strain TA100 were obtained only in fecal extracts of Sunset Yellow… Expand
10 Citations
Lack of genotoxic effect of food dyes amaranth, sunset yellow and tartrazine and their metabolites in the gut micronucleus assay in mice.
  • 99
In vivo genotoxicity assessment of sunset yellow and sodium benzoate in female rats
  • 7
  • Highly Influenced
Evaluation of a three‐exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals
  • 229
Toxicity of food colours and additives: A review
  • 5

References

SHOWING 1-10 OF 14 REFERENCES
Screening of food dyes for genotoxic activity.
  • 63
Mutagenicity studies of urine and faecal samples from rats treated orally with the food colourings Brown FK and Red 2G.
  • C. N. Edwards, R. Combes
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1984
  • 6
The significance of azo-reduction in the mutagenesis and carcinogenesis of azo dyes.
  • K. Chung
  • Chemistry, Medicine
  • Mutation research
  • 1983
  • 266
  • PDF
Mutagenicity testing of some commonly used dyes.
  • 187
  • PDF
...
1
2
...