Testing of saliva for antibodies to HIV-1.

  title={Testing of saliva for antibodies to HIV-1.},
  author={Nick Crofts and Scott Nicholson and Patrick Coghlan and Ian David Gust},
  volume={5 5},
To determine whether saliva is a potentially useful sample for screening for HIV infection when serum is not obtainable, saliva and serum samples from 50 HIV-infected and 50 uninfected subjects were tested for antibody to HIV-1 (anti-HIV-1) using a second-generation enzyme-linked immunosorbent assay (ELISA; Abbott) and prototype antibody-capture ELISA (Wellcome). Of saliva specimens from HIV-infected people, six gave negative results on the Abbott and one on the Wellcome assays; all specimens… CONTINUE READING