Testing by artificial intelligence: computational alternatives to the determination of mutagenicity.

@article{Klopman1992TestingBA,
  title={Testing by artificial intelligence: computational alternatives to the determination of mutagenicity.},
  author={Gilles Klopman and Herbert S. Rosenkranz},
  journal={Mutation research},
  year={1992},
  volume={272 1},
  pages={59-71}
}
In order to develop methods for evaluating the predictive performance of computer-driven structure-activity methods (SAR) as well as to determine the limits of predictivity, we investigated the behavior of two Salmonella mutagenicity data bases: (a) a subset from the Genetox Program and (b) one from the U.S. National Toxicology Program (NTP). For molecules… CONTINUE READING