Testing Lab-on-a-Chip Technology for Culturing Human Melanoma Cells under Simulated Microgravity

  title={Testing Lab-on-a-Chip Technology for Culturing Human Melanoma Cells under Simulated Microgravity},
  author={D. Przystupski and A. G{\'o}rska and O. Michel and A. Podwin and P. Sniadek and R. Łapczyński and J. Saczko and J. Kulbacka},
Simple Summary The main aim of this study was to investigate whether all-glass Lab-on-a-Chip (LOC) platforms can be applied to cancer cell research performed under simulated microgravity. For this purpose, we designed and constructed a 3D-clinostat—a device that allows us to investigate the effect of simulated microgravity (sµg) in biological studies. We used human keratinocytes HaCaT and skin melanoma A375 cells cultured on LOCs as a research model. Preliminary analyses included optimization… Expand
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