Testicular toxicity induced by single dosing of di- and mono-(2-ethylhexyl) phthalate in the rat.

@article{Teirlynck1988TesticularTI,
  title={Testicular toxicity induced by single dosing of di- and mono-(2-ethylhexyl) phthalate in the rat.},
  author={O. A. Teirlynck and Jean Kaufman and Marc G. Bogaert and Harry Roels},
  journal={Toxicology letters},
  year={1988},
  volume={40 1},
  pages={85-91}
}
The testicular toxicity of di-(2-ethylhexyl) phthalate (DEHP), a widely used plasticizer, and of its major metabolite, mono-(2-ethylhexyl) phthalate (MEHP), was assessed after a single dose in rats. Treatment with a single dose of 2.8 g/kg DEHP or 0.8 g/kg MEHP was sufficient to induce testicular atrophy as observed 7 days after dosing. Such a treatment had no effect on plasma FSH levels, and had varying effects on testicular zinc concentrations. After a single dose of 0.8 g/kg MEHP the… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
7 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-7 of 7 extracted citations

Similar Papers

Loading similar papers…