Testicular hyperthermia induces Unfolded Protein Response signaling activation in spermatocyte.

@article{Kim2013TesticularHI,
  title={Testicular hyperthermia induces Unfolded Protein Response signaling activation in spermatocyte.},
  author={Jung-Hak Kim and S Park and Tae-Shin Kim and Hyo-Jin Park and Junghyung Park and Bo Kyung Kim and Gyeong-Ryul Kim and Jin-Man Kim and Song Mei Huang and Jung-Il Chae and Choon-keun Park and Dong-Seok Lee},
  journal={Biochemical and biophysical research communications},
  year={2013},
  volume={434 4},
  pages={861-6}
}
The testes of most mammals are sensitive to temperature. To survive and adapt under conditions that promote endoplasmic reticulum (ER) stress such as heat shock, cells have a self-protective mechanism against ER stress that has been termed the "Unfolded Protein Response" (UPR). However, the cellular and molecular events underlying spermatogenesis with… CONTINUE READING