Testicular function in biotin-deficient adult rats.

@article{Paulose1989TesticularFI,
  title={Testicular function in biotin-deficient adult rats.},
  author={Chiramadathikudiyil Skaria Paulose and James Thliveris and Mohan Viswanathan and Krishnamurti Dakshinamurti},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={1989},
  volume={21 12},
  pages={
          661-5
        }
}
We have studied testicular function in the biotin-deficient rat biochemically and morphologically. Serum testosterone and luteinizing hormone (LH) levels were decreased significantly in the deficient rats. Administration of biotin or gonadotropins to the deficient rats reversed this decrease in serum testosterone. There was no difference in the serum cholesterol level between the control and biotin-deficient rats. A significant degree of sloughing of seminiferous tubule germinal epithelium was… 
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