Testicular biodistribution of silica-gold nanoparticles after intramuscular injection in mice.

@article{Leclerc2015TesticularBO,
  title={Testicular biodistribution of silica-gold nanoparticles after intramuscular injection in mice.},
  author={Lara Leclerc and J P Klein and Val{\'e}rie Forest and Delphine Boudard and Matteo Martini and J{\'e}r{\'e}mie Pourchez and M. Blanchin and Mich{\`e}le Cottier},
  journal={Biomedical microdevices},
  year={2015},
  volume={17 4},
  pages={66}
}
With the continuing development of nanomaterials, the assessment of their potential impact on human health, and especially human reproductive toxicity, is a major issue. The testicular biodistribution of nanoparticles remains poorly studied. This study investigated whether gold-silica nanoparticles could be detected in mouse testes after intramuscular injection, with a particular focus on their ability to cross the blood-testis barrier. To that purpose, well-characterized 70-nm gold core-silica… CONTINUE READING