Testicular atrophy associated with agenesis of the epididymis in the ACI rat.

@article{Marshall1982TesticularAA,
  title={Testicular atrophy associated with agenesis of the epididymis in the ACI rat.},
  author={Fray F. Marshall and Larry L. Ewing and Barry R. Zirkin and R C Cochran},
  journal={The Journal of urology},
  year={1982},
  volume={127 1},
  pages={155-8}
}
The male ACI rat has a congenital Wolffian duct defect manifested by unilateral agenesis of the kidney, ureter, seminal vesicle, ductus deferens, and most of the epididymis. In the adult the testis on the affected side is markedly smaller than the contralateral testis and spermatogenesis is absent. In addition, in vitro perfusion of the affected testis revealed significantly less testosterone secretion than did the contralateral testis. Moreover, electron microscopy revealed that the smooth… CONTINUE READING