Testicular and epididymal ADAMs: expression and function during fertilization

@article{Cho2012TesticularAE,
  title={Testicular and epididymal ADAMs: expression and function during fertilization},
  author={C. Cho},
  journal={Nature Reviews Urology},
  year={2012},
  volume={9},
  pages={550-560}
}
  • C. Cho
  • Published 2012
  • Biology, Medicine
  • Nature Reviews Urology
The disintegrin and metalloprotease domain-containing protein (ADAM) family of multidomain membrane proteins comprises at least 34 members in mammals. More than half of these proteins are expressed specifically or predominantly in mammalian testes and epididymis, implying their prominence in male reproduction. These reproductive ADAMs can be classified into three phylogenetic groups; designated I, II, and III. Each group displays remarkably contrasting features. Group I contains 11 ADAMs… Expand
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