Test-retest variability and reliability of 123I-IBZM SPECT measurement of striatal dopamine D2 receptor availability in healthy volunteers and influence of iterative reconstruction algorithms.

@article{Catafau2008TestretestVA,
  title={Test-retest variability and reliability of 123I-IBZM SPECT measurement of striatal dopamine D2 receptor availability in healthy volunteers and influence of iterative reconstruction algorithms.},
  author={Ana M. Catafau and Santiago Bullich and M{\'o}nica Dan{\'u}s and Maria M. Penengo and Albert Cot and Sergio Abanades and Mag{\'i} Farr{\'e} and Javier Pav{\'i}a and Dom{\`e}nec Ros},
  journal={Synapse},
  year={2008},
  volume={62 1},
  pages={62-9}
}
OBJECTIVE 123I-IBZM single photon emission computed tomography (SPECT) is a widely used method to measure D(2) receptor availability. However, test-retest variability and reliability have not been reported yet. This study aimed to further characterize 123I-IBZM SPECT in healthy volunteers (HVs), by assessing (1) pseudoequilibrium interval after bolus injection; (2) normal specific uptake ratio (SUR) values using filtered-backprojection (FBP); and the iterative reconstruction algorithm ordered… CONTINUE READING