Test performance characteristics of Anti-HEV IgG assays strongly influence hepatitis E seroprevalence estimates.

@article{Wenzel2013TestPC,
  title={Test performance characteristics of Anti-HEV IgG assays strongly influence hepatitis E seroprevalence estimates.},
  author={J{\"u}rgen J Wenzel and Julia Preiss and Mathias Schemmerer and Barbara Huber and Wolfgang Jilg},
  journal={The Journal of infectious diseases},
  year={2013},
  volume={207 3},
  pages={
          497-500
        }
}
Hepatitis E virus (HEV) seroprevalences of 0.3%-53% were reported from industrialized countries. Because these estimates may be influenced by detection assays, this study compares 3 frequently used tests for HEV detection: the MP Diagnostics HEV immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA), the Axiom Diagnostics HEV IgG enzyme immunoassay (EIA), and the Mikrogen recomLine HEV IgG assay. Sera from 200 healthy healthcare workers and 30 individuals with acute HEV infection were… CONTINUE READING

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