Test of blockers of AQP1 water permeability by a high-resolution method: no effects of tetraethylammonium ions or acetazolamide

@article{Sgaard2007TestOB,
  title={Test of blockers of AQP1 water permeability by a high-resolution method: no effects of tetraethylammonium ions or acetazolamide},
  author={Rikke S\ogaard and Thomas Zeuthen},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2007},
  volume={456},
  pages={285-292}
}
The effects of putative water channel blockers were tested on AQP1-expressing Xenopus laevis oocytes by a fast optical method with a time resolution of 1 s and a volume resolution of 20 pl. The oocytes were exposed to external hyposmolarity and the osmotic water permeability (L p) derived from the initial 10 s of volume change. For longer durations, the effective osmotic gradient across the membrane was reduced significantly because of dilution of the intracellular contents and of ion transport… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Acetazolamide inhibits osmotic water permeability by interaction with aquaporin-1.

Analytical biochemistry • 2006
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…