Test–retest variability of serotonin 5‐HT2A receptor binding measured with positron emission tomography and [18F]altanserin in the human brain

@article{Smith1998TestretestVO,
  title={Test–retest variability of serotonin 5‐HT2A receptor binding measured with positron emission tomography and [18F]altanserin in the human brain},
  author={Gwenn S. Smith and Julie C. Price and Brian J. Lopresti and Y. Huang and Norman R. Simpson and D. Holt and N. Scott Mason and Carolyn Cidis Meltzer and Robert A. Sweet and T. Nichols and D. Sashin and Chester A. Mathis},
  journal={Synapse},
  year={1998},
  volume={30}
}
  • Gwenn S. Smith, Julie C. Price, +9 authors Chester A. Mathis
  • Published 1998
  • Medicine, Psychology
  • Synapse
  • The role of serotonin in CNS function and in many neuropsychiatric diseases (e.g., schizophrenia, affective disorders, degenerative dementias) support the development of a reliable measure of serotonin receptor binding in vivo in human subjects. To this end, the regional distribution and intrasubject test–retest variability of the binding of [18F]altanserin were measured as important steps in the further development of [18F]altanserin as a radiotracer for positron emission tomography (PET… CONTINUE READING

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