Terumi Mukai and the riddle of deleterious mutation rates.

@article{Keightley1999TerumiMA,
  title={Terumi Mukai and the riddle of deleterious mutation rates.},
  author={Peter D. Keightley and Adam Eyre-Walker},
  journal={Genetics},
  year={1999},
  volume={153 2},
  pages={
          515-23
        }
}
DURING the 1960s and 1970s Terumi Mukai and gested, which was “the price paid by a species for its colleagues conducted some experiments that have capacity for further evolution” (Haldane 1937, p. 349). had a major impact in population and evolutionary geIn principle, estimation of U requires an unbiased way netics. Their quest was to estimate the genomic rate to measure the mutation rate in a random sample of and effects of deleterious mutations. However, recent the genes in the genome. The… CONTINUE READING

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