Tertiary Structure of Ribonuclease

@article{Kartha1967TertiarySO,
  title={Tertiary Structure of Ribonuclease},
  author={G. Kartha and J. Bello and D. Harker},
  journal={Nature},
  year={1967},
  volume={213},
  pages={862-865}
}
  • G. Kartha, J. Bello, D. Harker
  • Published 1967
  • Chemistry, Medicine
  • Nature
  • A model is proposed of the polypeptide chain in bovine pancreatic ribonuclease based on a 2 Å electron density map involving 7,294 reflexions and data from seven heavy atom derivatives. The molecule seems to be roughly kidney shaped with dimensions of about 38 × 28 × 22 Å with a deep depression in the middle of one side. The model disagrees with that based on a 5.5 Å map suggested by Dr. C. H. Carlisle et al. (Nature, 213, 557; 1967). 
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