Territrem and Butyrolactone Derivatives from a Marine-Derived Fungus Aspergillus Terreus

  title={Territrem and Butyrolactone Derivatives from a Marine-Derived Fungus Aspergillus
  author={Xu-hua Nong and Yi-Fei Wang and Xiao-Yong Zhang and Mu-Ping Zhou and Xin-ya Xu and Shu-hua Qi},
  booktitle={Marine drugs},
Seventeen lactones including eight territrem derivatives (1-8) and nine butyrolactone derivatives (9-17) were isolated from a marine-derived fungus Aspergillus terreus SCSGAF0162 under solid-state fermentation of rice. Compounds 1-3 and 9-10 were new, and their structures were elucidated by spectroscopic analysis. The acetylcholinesterase inhibitory activity and antiviral activity of compounds 1-17 were evaluated. Among them, compounds 1 and 2 showed strong inhibitory activity against… CONTINUE READING


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