Terrestrial gastropods (Helix spp) as sentinels of primary DNA damage for biomonitoring purposes: a validation study.

@article{Angeletti2013TerrestrialG,
  title={Terrestrial gastropods (Helix spp) as sentinels of primary DNA damage for biomonitoring purposes: a validation study.},
  author={Dario Angeletti and Claudia Sebbio and Claudio Carere and Roberta Cimmaruta and Giuseppe Nascetti and Gaetano Pepe and Pasquale Mosesso},
  journal={Environmental and molecular mutagenesis},
  year={2013},
  volume={54 3},
  pages={
          204-12
        }
}
We validated the alkaline comet assay in two species of land snail (Helix aspersa and Helix vermiculata) to test their suitability as sentinels for primary DNA damage in polluted environments. The study was conducted under the framework of a biomonitoring program for a power station in Central Italy that had recently been converted from oil to coal-fired plant. After optimizing test conditions, the comet assay was used to measure the % Tail DNA induced by in vitro exposure of hemocytes to… CONTINUE READING
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