BACKGROUND Ligularia kangtingensis, a species from the genus Ligularia (Compositae), is an indigenous plant in Southwest China and more than 20 species in this genus have been used as folk medicines in China. OBJECTIVE The chemical constituents of the whole plant of L. kangtingensis were studied. MATERIALS AND METHODS The dried whole plants were extracted with ethanol. Its chemical constituents were mainly isolated and purified by silica gel and Sephadex LH-20 column chromatography and their structures were identified on the basis of spectral analysis. RESULTS Twelve known terpenoids, including two monoterpenoids, five sesquiterpenoids and five triterpenoids, were isolated and identified from the whole plant of L. kangtingensis. CONCLUSION All of the 12 known compounds were isolated for the first time from L. kangtingensis.