Ternary-Responsive Drug Delivery with Activatable Dual Mode Contrast-Enhanced in Vivo Imaging.

@article{Ren2018TernaryResponsiveDD,
  title={Ternary-Responsive Drug Delivery with Activatable Dual Mode Contrast-Enhanced in Vivo Imaging.},
  author={Shuangshuang Ren and Jie Yang and Lan Ma and Xincong Li and Wenlei Wu and Chao Liu and Jian He and Leiying Miao},
  journal={ACS applied materials & interfaces},
  year={2018},
  volume={10 38},
  pages={
          31947-31958
        }
}
  • Shuangshuang Ren, Jie Yang, +5 authors Leiying Miao
  • Published in
    ACS applied materials…
    2018
  • Materials Science, Medicine
  • Designing a smart nanotheranostic system has recently attracted tremendous attention and is highly desirable for realizing targeted cancer therapy and early diagnosis. Herein we report the fabrication of smart nanotheranostic system using multiresponsive gatekeeping protocol of mesoporous silica nanoparticles (MSN). Acid, oxidative stress and redox sensitive manganese oxide (MnO x) coated superparamagnetic iron oxide nanoparticle (SPION) were employed as nanolids to regulate the camptothecin… CONTINUE READING

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