Terminator Detection by Support Vector Machine Utilizing a Stochastic Context-Free Grammar

Abstract

A 2-stage detector was designed to find rho-independent transcription terminators in the Escherichia coli genome. The detector includes a stochastic context free grammar (SCFG) component and a support vector machine (SVM) component. To find terminators, the SCFG searches the intergenic regions of nucleotide sequence for local matches to a terminator grammar… (More)

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