Termination at sTop2.


In this issue of Molecular Cell, Fachinetti et al. provide the first comprehensive map of replication termination sites (TERs) in Saccharomyces cerevisiae (Fachinetti et al., 2010). Strikingly, the majority of TERs are occupied by topoisomerase 2, which shields these regions against genomic instability.

DOI: 10.1016/j.molcel.2010.08.006

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@article{Alver2010TerminationAS, title={Termination at sTop2.}, author={Robert C Alver and Anja-Katrin Bielinsky}, journal={Molecular cell}, year={2010}, volume={39 4}, pages={487-9} }