Terlipressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotensin converting-enzyme inhibitors: a prospective, randomized, double-blinded, crossover study.

@article{Meersschaert2002TerlipressinephedrineVE,
  title={Terlipressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotensin converting-enzyme inhibitors: a prospective, randomized, double-blinded, crossover study.},
  author={Karoline Meersschaert and L. Brun and Maximilien Gourdin and St{\'e}phane Mouren and Mich{\`e}le Bertrand and Bruno Riou and Pierre Coriat},
  journal={Anesthesia and analgesia},
  year={2002},
  volume={94 4},
  pages={835-40, table of contents}
}
UNLABELLED In patients chronically treated with angiotensin converting-enzyme inhibitors (ACEI), typically selected doses of ephedrine do not always restore arterial blood pressure when anesthesia-induced hypotension occurs. We postulated that the administration of terlipressin, an agonist of the vasopressin system, with ephedrine more effectively restores pressure in this setting than the administration of ephedrine alone. This prospective, randomized, cross-over, double-blinded study compared… CONTINUE READING

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