Terbium-mediated footprinting probes a catalytic conformational switch in the antigenomic hepatitis delta virus ribozyme.

@article{Harris2004TerbiummediatedFP,
  title={Terbium-mediated footprinting probes a catalytic conformational switch in the antigenomic hepatitis delta virus ribozyme.},
  author={Dinari A. Harris and Rebecca A Tinsley and Nils G Walter},
  journal={Journal of molecular biology},
  year={2004},
  volume={341 2},
  pages={389-403}
}
The two forms of the hepatitis delta virus ribozyme are derived from the genomic and antigenomic RNA strands of the human hepatitis delta virus (HDV), where they serve a crucial role in pathogen replication by catalyzing site-specific self-cleavage reactions. The HDV ribozyme requires divalent metal ions for formation of its tertiary structure, consisting… CONTINUE READING