Teratozoospermia: spotlight on the main genetic actors in the human.

  title={Teratozoospermia: spotlight on the main genetic actors in the human.},
  author={Charles Coutton and Jessica Escoffier and Guillaume Martinez and Christophe Arnoult and Pierre F Ray},
  journal={Human reproduction update},
  volume={21 4},
BACKGROUND Male infertility affects >20 million men worldwide and represents a major health concern. Although multifactorial, male infertility has a strong genetic basis which has so far not been extensively studied. Recent studies of consanguineous families and of small cohorts of phenotypically homogeneous patients have however allowed the identification of a number of autosomal recessive causes of teratozoospermia. Homozygous mutations of aurora kinase C (AURKC) were first described to be… CONTINUE READING
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