Teratogenicity study of Scutellariae Radix in rats.

  title={Teratogenicity study of Scutellariae Radix in rats.},
  author={Sung Hoon Kim and Yeon Hee Kim and Sang Seop Han and Jae Kyung Roh},
  journal={Reproductive toxicology},
  volume={7 1},
This teratogenicity study was carried out in pregnant S.P.F. Sprague-Dawley female rats. These animals received for a period of 11 days, from day 7 to 17 of gestation, by daily oral administration, the water extract concentrates of the medicinal herb, Scutellariae Radix, at dose levels of 0.25 g/kg (group I), 12.49 g/kg (group II), and 24.98 g/kg (group III). Two-thirds of pregnant females in each group were sacrificed on day 20 of gestation and their fetuses were examined. The remaining dams… CONTINUE READING