Teratogenicity of di-n-butyltin dichloride in rats.


Pregnant rats were given di-n-butyltin dichloride (DBT) by gastric intubation at a dose of 0, 2.5, 5.0, 7.5 or 10.0 mg/kg on days 7-15 of pregnancy. Maternal toxicity occurred in the 7.5 and 10.0 mg/kg groups as evidenced by a significant increase in maternal death and decrease in food consumption and body weight gain. The incidence of fetuses with… (More)


Cite this paper

@article{Ema1991TeratogenicityOD, title={Teratogenicity of di-n-butyltin dichloride in rats.}, author={Mizue Ema and Takaharu Itami and H Kawasaki}, journal={Toxicology letters}, year={1991}, volume={58 3}, pages={347-56} }