Teratogenicity of 2-methoxyethanol applied as a single dermal dose to rats.

@article{Feuston1990TeratogenicityO2,
  title={Teratogenicity of 2-methoxyethanol applied as a single dermal dose to rats.},
  author={Maureen H Feuston and S L Kerstetter and Philip D. Wilson},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1990},
  volume={15 3},
  pages={448-56}
}
2-Methoxyethanol (2-ME) was applied as a single dermal dose on the backs of collared, pregnant Sprague-Dawley rats on Gestation Days (GD) 10, 11, 12, 13, or 14 at doses of 0 and 2000 mg/kg, and at doses of 0, 250, 500, and 1000 mg/kg on GD 12. Except for a transient loss in body weight observed the day after 2-ME administration, no signs of maternal… CONTINUE READING