Teratogenic effects of ethanol exposure on zebrafish visual system development.

@article{Arenzana2006TeratogenicEO,
  title={Teratogenic effects of ethanol exposure on zebrafish visual system development.},
  author={Francisco Javier Arenzana and Michael J Carvan and Jos{\'e} Aij{\'o}n and Rosario S{\'a}nchez-Gonz{\'a}lez and Rosario Ar{\'e}valo Ar{\'e}valo and Angel Porteros},
  journal={Neurotoxicology and teratology},
  year={2006},
  volume={28 3},
  pages={342-8}
}
Ethanol intake during pregnancy can produce a wide range of adverse effects on nervous system development including fetal alcohol syndrome (FAS). The most severe congenital malformation observed in newborns with FAS is cyclopia. In this study, we have exposed zebrafish embryos to different ethanol concentrations (2.4%, 1.5% or 1.0%) during eye morphogenesis in four zebrafish strains (AB, EK, GL and TL). In addition, we have studied the survival rate of the cyclopic animals to the end of larval… CONTINUE READING